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Cryo-EM reveals how adeno-associated virus engages its receptor AAVR and an investigation of the GPR108 ectodomain
(University of Missouri--Columbia, 2022)
-enveloped virus, the protein shell of AAV is responsible for all of the host interactions from cell entry to gene delivery. With further study of the AAV structure and how AAV engages with human cells and the immune system we hope to create a roadmap of the AAV...